Primary Ingredients
AppTrim-D is a proprietary formulation of amino acids and other dietary factors to support induction, maintenance, and enhancement of the specific neurotransmitter activity
involved in the physiology of obesity. The formulation consists of nonessential and essential amino acids, L-Glutamic Acid, Choline Bitartrate, L-Histidine HCL, L-Tyrosine, LSerine,
Whey Protein Isolate (Milk), Griffonia Seed Extract and Grape Seed Extract. These ingredients fall into the classification of Generally Recognized as Safe (GRAS) as
defined by the Food and Drug Administration (FDA) (Sections 201(s) and 409 of the Federal Food, Drug, and Cosmetic Act). A GRAS substance is distinguished from a food
additive on the basis of the common knowledge about the safety of the substance for its intended use. The standard for an ingredient to achieve GRAS status requires not only
technical demonstration of non-toxicity and safety, but also general recognition of safety through widespread usage and agreement of that safety by experts in the field. Many
ingredients have been determined by the FDA to be GRAS, and are listed as such by regulation, in Volume 21 Code of Federal Regulations (CFR) Sections 182, 184, and 186
Amino Acids
Amino Acids are the building blocks of protein and are GRAS listed as they have been safely ingested by humans for thousands of years. The formulations of the amino acids in
AppTrim-D are equivalent to those found in the usual human diet. Obese patients may require an increased amount of certain amino acids that cannot be obtained from normal
diet alone. Tryptophan, for example, is an obligatory amino acid. The body cannot make tryptophan and must obtain tryptophan from the diet. Tryptophan is needed to produce
serotonin. Serotonin is required to reduce appetite and carbohydrate cravings. Obese and morbidly obese patients frequently have altered serotonin metabolism. Some obese
and morbidly obese patients have a resistance to the use of tryptophan that is similar to the mechanism found in insulin resistance. Some obese and morbidly obese patients
cannot acquire sufficient tryptophan from the diet without ingesting a prohibitively large amount of calories, particularly calories from protein.
Other Ingredients
AppTrim-D contains the following “inactive” or other ingredients, as fillers, excipients, and colorings: Gelatin, vegetable magnesium stearate, silicon dioxide, lac-resin, carmine.
