But beyond the risk of gluten contamination, a gluten-free diet does not appear sufficient for repairing intestinal damage. In one study from 2010 of 241 subjects with celiac disease, only 35% of subjects saw mucosal recovery of the small intestine after 2 years of following a gluten-free diet, and only 66% saw mucosal recovery after 5 years of eating a gluten-free diet. Another study from 2009 examined 465 celiac subjects who adhered to a gluten-free diet for 16 months and found that total restoration of the intestinal damage inflicted by gluten was exceptionally rare (roughly 8%) in adult celiac patients despite following a gluten-free diet.4 These findings suggest that while a gluten-free diet can help to prevent further damage, the avoidance of gluten alone is not sufficient for total gut restoration.
A combination of probiotic spores and yeast can effectively support intestinal health and barrier function. Saccharomyces boulardii is a probiotic yeast that can help support digestive health by producing lactate, B vitamins, and targeted antimicrobials to defend against pathogenic gut infections. S. boulardii has also been shown to be immunoprotective through the upregulation of IgA and IgG secretions in the intestines. Bacillus coagulans and Bacillus subtilis are spore-forming probiotics that are naturally designed to survive digestion, support intestinal barrier function, and enhance the microbial diversity of the gut microbiome.
B. coagulans is very unique in that it possesses characteristics of both Bacillus and Lactobacillus genera. It functions as a lactic acid-producing bacterium with the protection and survivability of a Bacillus spore. Bacillus subtilis HU58™ provides potent immune modulation and has been shown to reduce pro-inflammatory cytokines IL-6 and TNF and significantly increase the production of short-chain fatty acids (SCFA) such as butyrate, acetate, and propionate in the gut. Butyrate is the major energy source for colonocytes and has been studied for its role in nourishing the colonic mucosa.
A recent study published in Scientific Reports concluded that microbially-derived byproducts like butyrate and lactate can be used to modulate the epithelial response to gluten by improving barrier function and reducing gliadin induced cytokine secretion.When it comes to facing the dangers of gluten, WheatRescue™ is here to save the day. WheatRescue™ offers complete digestive support, superior protection, and peace of mind concerning gluten.